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To step or not to step? How biochemistry and mechanics influence processivity in Kinesin and Eg5

Conventional kinesin and Eg5 are essential nanoscale motor proteins. Single-molecule and presteady-state kinetic experiments indicate that both motors use similar strategies to generate movement along microtubules, despite having distinctly different in vivo functions. Single molecules of kinesin, a...

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Autors principals: Valentine, Megan T, Gilbert, Susan P
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270473/
https://ncbi.nlm.nih.gov/pubmed/17188855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2006.12.011
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