DJ-1 Modulates α-Synuclein Aggregation State in a Cellular Model of Oxidative Stress: Relevance for Parkinson's Disease and Involvement of HSP70

BACKGROUND: Parkinson's disease (PD) is a neurodegenerative pathology whose molecular etiopathogenesis is not known. Novel contributions have come from familial forms of PD caused by alterations in genes with apparently unrelated physiological functions. The gene coding for alpha-synuclein (α-s...

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Bibliographic Details
Main Authors: Batelli, Sara, Albani, Diego, Rametta, Raffaela, Polito, Letizia, Prato, Francesca, Pesaresi, Marzia, Negro, Alessandro, Forloni, Gianluigi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2008
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270347/
https://ncbi.nlm.nih.gov/pubmed/18382667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001884
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