DJ-1 Modulates α-Synuclein Aggregation State in a Cellular Model of Oxidative Stress: Relevance for Parkinson's Disease and Involvement of HSP70

BACKGROUND: Parkinson's disease (PD) is a neurodegenerative pathology whose molecular etiopathogenesis is not known. Novel contributions have come from familial forms of PD caused by alterations in genes with apparently unrelated physiological functions. The gene coding for alpha-synuclein (α-s...

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Detalhes bibliográficos
Main Authors: Batelli, Sara, Albani, Diego, Rametta, Raffaela, Polito, Letizia, Prato, Francesca, Pesaresi, Marzia, Negro, Alessandro, Forloni, Gianluigi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270347/
https://ncbi.nlm.nih.gov/pubmed/18382667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001884
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