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A single residue contributes to the difference between Kir4.1 and Kir1.1 channels in pH sensitivity, rectification and single channel conductance

1. Kir1.1 and Kir4.1 channels may be involved in the maintenance of pH and K(+) homeostasis in renal epithelial cells and CO(2) chemoreception in brainstem neurons. To understand the molecular determinants for their characteristic differences, the structure-function relationship was studied using si...

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Detalhes bibliográficos
Main Authors: Xu, Haoxing, Yang, Zhenjiang, Cui, Ningren, Chanchevalap, Sengthong, Valesky, Walter W, Jiang, Chun
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270133/
https://ncbi.nlm.nih.gov/pubmed/11034617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.00267.x
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