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Opposite effects of pH on open-state probability and single channel conductance of Kir4.1 channels

1. A decrease in intracellular pH (pH(i)) inhibits whole-cell Kir4.1 currents. To understand channel biophysical properties underlying this inhibition, single channel Kir4.1 currents were studied in inside-out patches using symmetric concentrations of K(+) applied to each side of the plasma membrane...

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Autores principales: Yang, Zhenjiang, Jiang, Chun
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269628/
https://ncbi.nlm.nih.gov/pubmed/10545154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.00921.x
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