A single residue contributes to the difference between Kir4.1 and Kir1.1 channels in pH sensitivity, rectification and single channel conductance

1. Kir1.1 and Kir4.1 channels may be involved in the maintenance of pH and K(+) homeostasis in renal epithelial cells and CO(2) chemoreception in brainstem neurons. To understand the molecular determinants for their characteristic differences, the structure-function relationship was studied using si...

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Autors principals: Xu, Haoxing, Yang, Zhenjiang, Cui, Ningren, Chanchevalap, Sengthong, Valesky, Walter W, Jiang, Chun
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2000
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270133/
https://ncbi.nlm.nih.gov/pubmed/11034617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.00267.x
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