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Biophysical and Molecular Mechanisms Underlying the Modulation of Heteromeric Kir4.1–Kir5.1 Channels by Co(2) and Ph

CO(2) chemoreception may be related to modulation of inward rectifier K(+) channels (Kir channels) in brainstem neurons. Kir4.1 is expressed predominantly in the brainstem and inhibited during hypercapnia. Although the homomeric Kir4.1 only responds to severe intracellular acidification, coexpressio...

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Autors principals: Yang, Zhenjiang, Xu, Haoxing, Cui, Ningren, Qu, Zhiqiang, Chanchevalap, Sengthong, Shen, Wangzhen, Jiang, Chun
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229613/
https://ncbi.nlm.nih.gov/pubmed/10871638
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