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Lidocaine induces a slow inactivated state in rat skeletal muscle sodium channels

1. Local anaesthetics such as lidocaine (lignocaine) interact with sodium channels in a manner that is exquisitely sensitive to the voltage-dependent conformational state of the ion channel. When depolarized in the presence of lidocaine, sodium channels assume a long-lived quiescent state. Although...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chen, Zhenhui, Ong, Boon-Hooi, Kambouris, Nicholas G, Marbán, Eduardo, Tomaselli, Gordon F, Balser, Jeffrey R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Science Inc 2000
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269847/
https://ncbi.nlm.nih.gov/pubmed/10747182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.t01-1-00037.x
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