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Peroxynitrite is a positive inotropic agent in atrial and ventricular fibres of the frog heart

1. We report opposite inotropic effects of NO donors in frog cardiac fibres. The negative effect, elicited by either 3-morpholino-sydnonimine (SIN-1) or S-nitroso-N-acetyl-penicillamine (SNAP), involved cyclic GMP (cGMP) production. However, SIN-1, unlike SNAP, could elicit a positive effect, in a s...

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書目詳細資料
Main Authors: Chesnais, Jean-Michel, Fischmeister, Rodolphe, Méry, Pierre-François
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269669/
https://ncbi.nlm.nih.gov/pubmed/10581309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.00375.x
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