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Positive and negative inotropic effects of NO donors in atrial and ventricular fibres of the frog heart

1. The cardiac effects of the NO donors sodium nitroprusside (SNP), S-nitroso-N-acetyl-penicillamine (SNAP) and 3-morpholino-sydnonimine (SIN-1) were studied in frog fibres to evaluate the contribution of cyclic GMP-dependent mechanisms. 2. SNP and SNAP (0·1-100 μM) reduced the force of contraction...

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Detalhes bibliográficos
Main Authors: Chesnais, Jean-Michel, Fischmeister, Rodolphe, Méry, Pierre-François
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269428/
https://ncbi.nlm.nih.gov/pubmed/10381591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.0449p.x
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