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Peroxynitrite is a positive inotropic agent in atrial and ventricular fibres of the frog heart

1. We report opposite inotropic effects of NO donors in frog cardiac fibres. The negative effect, elicited by either 3-morpholino-sydnonimine (SIN-1) or S-nitroso-N-acetyl-penicillamine (SNAP), involved cyclic GMP (cGMP) production. However, SIN-1, unlike SNAP, could elicit a positive effect, in a s...

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Detalhes bibliográficos
Main Authors: Chesnais, Jean-Michel, Fischmeister, Rodolphe, Méry, Pierre-François
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269669/
https://ncbi.nlm.nih.gov/pubmed/10581309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.00375.x
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