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Two-photon imaging of intratumoral CD8(+) T cell cytotoxic activity during adoptive T cell therapy in mice

CTLs have the potential to attack tumors, and adoptive transfer of CTLs can lead to tumor regression in mouse models and human clinical settings. However, the dynamics of tumor cell elimination during efficient T cell therapy is unknown, and it is unclear whether CTLs act directly by destroying tumo...

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Hlavní autoři: Breart, Béatrice, Lemaître, Fabrice, Celli, Susanna, Bousso, Philippe
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268880/
https://ncbi.nlm.nih.gov/pubmed/18357341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34388
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