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RelB is the NF-κB subunit downstream of NIK responsible for osteoclast differentiation
NF-κB inducing kinase (NIK) is required for osteoclastogenesis in response to pathologic stimuli, and its loss leads to functional blockade of both alternative and classical NF-κB caused by cytoplasmic retention by p100. We now show that deletion of p100 restores the capacity of NIK-deficient osteoc...
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| Hlavní autoři: | , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268780/ https://ncbi.nlm.nih.gov/pubmed/18322009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708576105 |
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