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NIK Stabilization in Osteoclasts Results in Osteoporosis and Enhanced Inflammatory Osteolysis

BACKGROUND: Maintenance of healthy bone requires the balanced activities of osteoclasts (OCs), which resorb bone, and osteoblasts, which build bone. Disproportionate action of OCs is responsible for the bone loss associated with postmenopausal osteoporosis and rheumatoid arthritis. NF-κB inducing ki...

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Библиографические подробности
Главные авторы: Yang, Chang, McCoy, Kathleen, Davis, Jennifer L., Schmidt-Supprian, Marc, Sasaki, Yoshiteru, Faccio, Roberta, Novack, Deborah Veis
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975662/
https://ncbi.nlm.nih.gov/pubmed/21151480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015383
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