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NIK Stabilization in Osteoclasts Results in Osteoporosis and Enhanced Inflammatory Osteolysis
BACKGROUND: Maintenance of healthy bone requires the balanced activities of osteoclasts (OCs), which resorb bone, and osteoblasts, which build bone. Disproportionate action of OCs is responsible for the bone loss associated with postmenopausal osteoporosis and rheumatoid arthritis. NF-κB inducing ki...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975662/ https://ncbi.nlm.nih.gov/pubmed/21151480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015383 |
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