NIK Stabilization in Osteoclasts Results in Osteoporosis and Enhanced Inflammatory Osteolysis

BACKGROUND: Maintenance of healthy bone requires the balanced activities of osteoclasts (OCs), which resorb bone, and osteoblasts, which build bone. Disproportionate action of OCs is responsible for the bone loss associated with postmenopausal osteoporosis and rheumatoid arthritis. NF-κB inducing ki...

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Autores principales: Yang, Chang, McCoy, Kathleen, Davis, Jennifer L., Schmidt-Supprian, Marc, Sasaki, Yoshiteru, Faccio, Roberta, Novack, Deborah Veis
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975662/
https://ncbi.nlm.nih.gov/pubmed/21151480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015383
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