Functional interactions among Orai1, TRPCs, and STIM1 suggest a STIM-regulated heteromeric Orai/TRPC model for SOCE/Icrac channels

Receptor-operated Ca(2+) entry (ROCE) and store-operated Ca(2+) entry (SOCE) into cells are functions performed by all higher eukaryotic cells, and their impairment is life-threatening. The main molecular components of this pathway appear to be known. However, the molecular make-up of channels media...

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Bibliografiske detaljer
Main Authors: Liao, Yanhong, Erxleben, Christian, Abramowitz, Joel, Flockerzi, Veit, Zhu, Michael Xi, Armstrong, David L., Birnbaumer, Lutz
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268556/
https://ncbi.nlm.nih.gov/pubmed/18287061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712288105
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