Single-Cell, Phosphoepitope-Specific Analysis Demonstrates Cell Type- and Pathway-Specific Dysregulation of Jak/STAT and MAPK Signaling Associated with In Vivo Human Immunodeficiency Virus Type 1 Infection

Despite extensive evidence of cell signaling alterations induced by human immunodeficiency virus type 1 (HIV-1) in vitro, the relevance of these changes to the clinical and/or immunologic status of HIV-1-infected individuals is often unclear. As such, mapping the details of cell type-specific degrad...

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Detalhes bibliográficos
Main Authors: Lee, Andrew W., Sharp, Elizabeth R., O'Mahony, Alison, Rosenberg, Michael G., Israelski, Dennis M., Nolan, Garry P., Nixon, Douglas F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268489/
https://ncbi.nlm.nih.gov/pubmed/18216116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01582-07
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