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Regulation of MDMX Expression by Mitogenic Signaling
MDMX is an important regulator of p53 transcriptional activity and stress response. MDMX overexpression and gene amplification are implicated in p53 inactivation and tumor development. Unlike MDM2, MDMX is not inducible by p53, and little is known about its regulation at the transcriptional level. W...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268405/ https://ncbi.nlm.nih.gov/pubmed/18172009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01633-07 |
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