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Regulation of MDMX Expression by Mitogenic Signaling

MDMX is an important regulator of p53 transcriptional activity and stress response. MDMX overexpression and gene amplification are implicated in p53 inactivation and tumor development. Unlike MDM2, MDMX is not inducible by p53, and little is known about its regulation at the transcriptional level. W...

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Detalhes bibliográficos
Main Authors: Gilkes, Daniele M., Pan, Yu, Coppola, Domenico, Yeatman, Timothy, Reuther, Gary W., Chen, Jiandong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268405/
https://ncbi.nlm.nih.gov/pubmed/18172009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01633-07
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