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A systems biology approach to prediction of oncogenes and molecular perturbation targets in B-cell lymphomas

The computational identification of oncogenic lesions is still a key open problem in cancer biology. Although several methods have been proposed, they fail to model how such events are mediated by the network of molecular interactions in the cell. In this paper, we introduce a systems biology approa...

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Detalhes bibliográficos
Main Authors: Mani, Kartik M, Lefebvre, Celine, Wang, Kai, Lim, Wei Keat, Basso, Katia, Dalla-Favera, Riccardo, Califano, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267731/
https://ncbi.nlm.nih.gov/pubmed/18277385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2008.2
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