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ZIP4H (TEX11) Deficiency in the Mouse Impairs Meiotic Double Strand Break Repair and the Regulation of Crossing Over

We have recently shown that hypomorphic Mre11 complex mouse mutants exhibit defects in the repair of meiotic double strand breaks (DSBs). This is associated with perturbation of synaptonemal complex morphogenesis, repair and regulation of crossover formation. To further assess the Mre11 complex'...

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Bibliografske podrobnosti
Main Authors: Adelman, Carrie A., Petrini, John H. J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267488/
https://ncbi.nlm.nih.gov/pubmed/18369460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000042
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