Excess Single-Stranded DNA Inhibits Meiotic Double-Strand Break Repair

During meiosis, self-inflicted DNA double-strand breaks (DSBs) are created by the protein Spo11 and repaired by homologous recombination leading to gene conversions and crossovers. Crossover formation is vital for the segregation of homologous chromosomes during the first meiotic division and requir...

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Bibliographic Details
Main Authors: Johnson, Rebecca, Borde, Valérie, Neale, Matthew J, Bishop-Bailey, Anna, North, Matthew, Harris, Sheila, Nicolas, Alain, Goldman, Alastair S. H
Format: Artigo
Language:Inglês
Published: Public Library of Science 2007
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2098809/
https://ncbi.nlm.nih.gov/pubmed/18081428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030223
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