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ZIP4H (TEX11) Deficiency in the Mouse Impairs Meiotic Double Strand Break Repair and the Regulation of Crossing Over
We have recently shown that hypomorphic Mre11 complex mouse mutants exhibit defects in the repair of meiotic double strand breaks (DSBs). This is associated with perturbation of synaptonemal complex morphogenesis, repair and regulation of crossover formation. To further assess the Mre11 complex'...
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Auteurs principaux: | , |
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Format: | Artigo |
Langue: | Inglês |
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Public Library of Science
2008
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2267488/ https://ncbi.nlm.nih.gov/pubmed/18369460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000042 |
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