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ZIP4H (TEX11) Deficiency in the Mouse Impairs Meiotic Double Strand Break Repair and the Regulation of Crossing Over

We have recently shown that hypomorphic Mre11 complex mouse mutants exhibit defects in the repair of meiotic double strand breaks (DSBs). This is associated with perturbation of synaptonemal complex morphogenesis, repair and regulation of crossover formation. To further assess the Mre11 complex'...

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Main Authors: Adelman, Carrie A., Petrini, John H. J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267488/
https://ncbi.nlm.nih.gov/pubmed/18369460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000042
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