NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-κB and JNK pathways by inducing reactive oxygen species production

NOD-like receptors (NLRs) are a family of intracellular sensors of microbial- or danger-associated molecular patterns. Here, we report the identification of NLRX1, which is a new member of the NLR family that localizes to the mitochondria. NLRX1 alone failed to trigger most of the common signalling...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tattoli, Ivan, Carneiro, Leticia A, Jéhanno, Muguette, Magalhaes, Joao G, Shu, Youmin, Philpott, Dana J, Arnoult, Damien, Girardin, Stephen E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Scientific Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267388/
https://ncbi.nlm.nih.gov/pubmed/18219313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401161
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados