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An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix
NLRX1 is the only member of the Nod-like receptor (NLR) family that is targeted to the mitochondria, and its overexpression induces the generation of reactive oxygen species (ROS), thus impacting on NFκB- and JNK-dependent signaling cascades. In addition, NLRX1 has been shown to interact with MAVS (...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Company of Biologists
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2871076/ https://ncbi.nlm.nih.gov/pubmed/19692591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.051193 |
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