Murine Nod1 but not its human orthologue mediates innate immune detection of tracheal cytotoxin

Tracheal cytotoxin (TCT) was originally described as the minimal effector that was able to reproduce the cytotoxic response of Bordetella pertussis on ciliated epithelial cells. This molecule triggers pleiotropic effects such as immune stimulation or slow-wave sleep modulation. Further characterizat...

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Detalhes bibliográficos
Main Authors: Magalhaes, Joao Gamelas, Philpott, Dana J, Nahori, Marie-Anne, Jéhanno, Muguette, Fritz, Joerg, Bourhis, Lionel Le, Viala, Jérôme, Hugot, Jean-Pierre, Giovannini, Marco, Bertin, John, Lepoivre, Michel, Mengin-Lecreulx, Dominique, Sansonetti, Philippe J, Girardin, Stephen E
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Scientific Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369207/
https://ncbi.nlm.nih.gov/pubmed/16211083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400552
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