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Differential regulation of class IA phosphoinositide 3-kinase catalytic subunits p110α and β by protease-activated receptor 2 and β-arrestins
PAR-2 (protease-activated receptor 2) is a GPCR (G-protein-coupled receptor) that can elicit both G-protein-dependent and -independent signals. We have shown previously that PAR-2 simultaneously promotes Gαq/Ca(2+)-dependent activation and β-arrestin-1-dependent inhibition of class IA PI3K (phosphoi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2267348/ https://ncbi.nlm.nih.gov/pubmed/17680774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070483 |
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