Non-hypertensive tetraPEGylated canine haemoglobin: correlation between PEGylation, O(2) affinity and tissue oxygenation

TetraPEGylated canine Hb, [SP (succinimidophenyl)-PEG5K](4)-canine-Hb, with PEGylation at its four reactive cysteine residues (α(111) and β(93)) has been prepared and characterized. The hydrodynamic volume and the molecular radius of (SP-PEG5K)(4)-canine-Hb are intermediate to those of di- and hexaP...

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Bibliografiset tiedot
Päätekijät: Acharya, Seetharama A., Acharya, Vivek N., Kanika, Nirmala Devi, Tsai, Amy G., Intaglietta, Marcos, Manjula, Belur N.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Portland Press Ltd. 2007
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267292/
https://ncbi.nlm.nih.gov/pubmed/17425516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070238
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