Dissociation of local nitric oxide concentration and vasoconstriction in the presence of cell-free hemoglobin oxygen carriers

Cell-free hemoglobin's (CFH) high affinity for nitric oxide (NO) could limit CFH's use as an oxygen-carrying blood replacement fluid because it scavenges NO, causing vasoconstriction and hypertension. However, the extent to which perivascular NO levels change following intravascular admini...

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Detalhes bibliográficos
Main Authors: Tsai, Amy G., Cabrales, Pedro, Manjula, Belur N., Acharya, Seetharama A., Winslow, Robert M., Intaglietta, Marcos
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Transfusion Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895434/
https://ncbi.nlm.nih.gov/pubmed/16857991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-02-005272
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