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Reversal of hemoglobin-induced vasoconstriction with sustained release of nitric oxide
Erythrocyte free hemoglobin (Hb) induces vasoconstriction due to nitric oxide (NO) scavenging, limiting the NO available for vascular smooth muscle. The central objective of this study was to restore NO bioavailability using long-lived circulating NO-releasing nanoparticles (NO-np) to reverse the va...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Physiological Society
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3023241/ https://ncbi.nlm.nih.gov/pubmed/21057038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00665.2010 |
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