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Reversal of hemoglobin-induced vasoconstriction with sustained release of nitric oxide

Erythrocyte free hemoglobin (Hb) induces vasoconstriction due to nitric oxide (NO) scavenging, limiting the NO available for vascular smooth muscle. The central objective of this study was to restore NO bioavailability using long-lived circulating NO-releasing nanoparticles (NO-np) to reverse the va...

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Autori principali: Cabrales, Pedro, Han, George, Nacharaju, Parimala, Friedman, Adam J., Friedman, Joel M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023241/
https://ncbi.nlm.nih.gov/pubmed/21057038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00665.2010
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