Role of complement C5a in mechanical inflammatory hypernociception: potential use of C5a receptor antagonists to control inflammatory pain

BACKGROUND AND PURPOSE: C5a, a complement activation product, exhibits a broad spectrum of inflammatory activities particularly neutrophil chemoattraction. Herein, the role of C5a in the genesis of inflammatory hypernociception was investigated in rats and mice using the specific C5a receptor antago...

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Bibliographic Details
Main Authors: Ting, E, Guerrero, A T G, Cunha, T M, Verri, W A, Taylor, S M, Woodruff, T M, Cunha, F Q, Ferreira, S H
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2007
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Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267274/
https://ncbi.nlm.nih.gov/pubmed/18084313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707640
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