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Atorvastatin inhibits inflammatory hypernociception

BACKGROUND AND PURPOSE: Atorvastatin is an inhibitor of the enzyme 3-hydroxyl-3-methylglutaryl coenzyme A reductase used to prevent coronary heart disease. We have studied the analgesic effect of atorvastatin in inflammatory models in which a sequential release of mediators (bradykinin, (BK), tumour...

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Detalhes bibliográficos
Main Authors: Santodomingo-Garzón, T, Cunha, T M, Verri, W A, Valério, D A R, Parada, C A, Poole, S, Ferreira, S H, Cunha, F Q
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1629407/
https://ncbi.nlm.nih.gov/pubmed/16865092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706836
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