Role of complement C5a in mechanical inflammatory hypernociception: potential use of C5a receptor antagonists to control inflammatory pain

BACKGROUND AND PURPOSE: C5a, a complement activation product, exhibits a broad spectrum of inflammatory activities particularly neutrophil chemoattraction. Herein, the role of C5a in the genesis of inflammatory hypernociception was investigated in rats and mice using the specific C5a receptor antago...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ting, E, Guerrero, A T G, Cunha, T M, Verri, W A, Taylor, S M, Woodruff, T M, Cunha, F Q, Ferreira, S H
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2007
Sujets:
Research Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267274/
https://ncbi.nlm.nih.gov/pubmed/18084313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707640
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