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In Silico Chaperonin-Like Cycle Helps Folding of Proteins for Structure Prediction

Currently, one of the most serious problems in protein-folding simulations for de novo structure prediction is conformational sampling of medium-to-large proteins. In vivo, folding of these proteins is mediated by molecular chaperones. Inspired by the functions of chaperonins, we designed a simple c...

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書誌詳細
主要な著者: Furuta, Tadaomi, Fujitsuka, Yoshimi, Chikenji, George, Takada, Shoji
フォーマット: Artigo
言語:Inglês
出版事項: The Biophysical Society 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267155/
https://ncbi.nlm.nih.gov/pubmed/18178656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.115261
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