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Competition between Protein Folding and Aggregation with Molecular Chaperones in Crowded Solutions: Insight from Mesoscopic Simulations

The living cell is inherently crowded with proteins and macromolecules. To avoid aggregation of denatured proteins in the living cell, molecular chaperones play important roles. Here we introduce a simple model to describe crowded protein solutions with chaperone-like species based on a dynamic dens...

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書目詳細資料
Main Authors: Kinjo, Akira R., Takada, Shoji
格式: Artigo
語言:Inglês
出版: Biophysical Society 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303659/
https://ncbi.nlm.nih.gov/pubmed/14645047
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