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Competition between Protein Folding and Aggregation with Molecular Chaperones in Crowded Solutions: Insight from Mesoscopic Simulations
The living cell is inherently crowded with proteins and macromolecules. To avoid aggregation of denatured proteins in the living cell, molecular chaperones play important roles. Here we introduce a simple model to describe crowded protein solutions with chaperone-like species based on a dynamic dens...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Biophysical Society
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1303659/ https://ncbi.nlm.nih.gov/pubmed/14645047 |
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