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Competition between Protein Folding and Aggregation with Molecular Chaperones in Crowded Solutions: Insight from Mesoscopic Simulations

The living cell is inherently crowded with proteins and macromolecules. To avoid aggregation of denatured proteins in the living cell, molecular chaperones play important roles. Here we introduce a simple model to describe crowded protein solutions with chaperone-like species based on a dynamic dens...

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Detalhes bibliográficos
Main Authors: Kinjo, Akira R., Takada, Shoji
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303659/
https://ncbi.nlm.nih.gov/pubmed/14645047
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