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In Silico Chaperonin-Like Cycle Helps Folding of Proteins for Structure Prediction
Currently, one of the most serious problems in protein-folding simulations for de novo structure prediction is conformational sampling of medium-to-large proteins. In vivo, folding of these proteins is mediated by molecular chaperones. Inspired by the functions of chaperonins, we designed a simple c...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2267155/ https://ncbi.nlm.nih.gov/pubmed/18178656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.115261 |
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