Cancer Regression in Patients After Transfer of Genetically Engineered Lymphocytes

Through the adoptive transfer of lymphocytes after host immunodepletion, it is possible to mediate objective cancer regression in human patients with metastatic melanoma. However, the generation of tumor-specific T cells in this mode of immunotherapy is often limiting. Here we report the ability to...

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Bibliografische gegevens
Hoofdauteurs: Morgan, Richard A., Dudley, Mark E., Wunderlich, John R., Hughes, Marybeth S., Yang, James C., Sherry, Richard M., Royal, Richard E., Topalian, Suzanne L., Kammula, Udai S., Restifo, Nicholas P., Zheng, Zhili, Nahvi, Azam, de Vries, Christiaan R., Rogers-Freezer, Linda J., Mavroukakis, Sharon A., Rosenberg, Steven A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267026/
https://ncbi.nlm.nih.gov/pubmed/16946036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1129003
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