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Effects of Exogenous Leptin on Satiety and Satiation in Patients with Lipodystrophy and Leptin Insufficiency

To examine leptin’s role in human appetite regulation, we studied recombinant methionyl human leptin’s effects on satiation and satiety in a model of leptin insufficiency, lipodystrophy. Eight females with hypoleptinemia and lipodystrophy were given sc injections of A-100 (maximal dose, 200% of that...

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Main Authors: McDuffie, Jennifer R., Riggs, Patti A., Calis, Karim A., Freedman, Renee J., Oral, Elif A., DePaoli, Alex M., Yanovski, Jack A.
Formato: Artigo
Idioma:Inglês
Publicado: 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266890/
https://ncbi.nlm.nih.gov/pubmed/15356018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2003-031868
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