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Effects of Exogenous Leptin on Satiety and Satiation in Patients with Lipodystrophy and Leptin Insufficiency

To examine leptin’s role in human appetite regulation, we studied recombinant methionyl human leptin’s effects on satiation and satiety in a model of leptin insufficiency, lipodystrophy. Eight females with hypoleptinemia and lipodystrophy were given sc injections of A-100 (maximal dose, 200% of that...

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主要な著者: McDuffie, Jennifer R., Riggs, Patti A., Calis, Karim A., Freedman, Renee J., Oral, Elif A., DePaoli, Alex M., Yanovski, Jack A.
フォーマット: Artigo
言語:Inglês
出版事項: 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266890/
https://ncbi.nlm.nih.gov/pubmed/15356018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2003-031868
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