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Atm is a Negative Regulator of Intestinal Neoplasia
The ATM (Ataxia telangiectasia mutated) gene has been implicated as an early barrier to the growth and progression of incipient solid tumors. Here, we show that germline nullizygosity for the mouse Atm gene significantly increases the proliferative index, net growth rate, and multiplicity of intesti...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2266837/ https://ncbi.nlm.nih.gov/pubmed/17700532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210708 |
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