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Localized gene action controlling intestinal neoplasia in mice

Mice heterozygous for the Apc(Min) (Min) mutation develop adenomas throughout the intestinal tract. Apc is believed to be involved in cell migration, adhesion, and polarity. Adenoma multiplicity and growth rate are modulated by an unlinked modifier locus, Mom1. The secretory phospholipase Pla2g2a is...

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Autors principals: Gould, Karen A., Dove, William F.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC20869/
https://ncbi.nlm.nih.gov/pubmed/9159163
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