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Modeling NF2 with human arachnoidal and meningioma cell culture systems: NF2 silencing reflects the benign character of tumor growth

Meningiomas, common tumors arising from arachnoidal cells of the meninges, may occur sporadically, or in association with the inherited disorder, neurofibromatosis 2 (NF2). Most sporadic meningiomas result from NF2 inactivation, resulting in loss of tumor suppressor merlin, implicated in regulating...

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Detalhes bibliográficos
Main Authors: James, Marianne F., Lelke, Johanna M., MacCollin, Mia, Plotkin, Scott R., Stemmer-Rachamimov, Anat O., Ramesh, Vijaya, Gusella, James F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266821/
https://ncbi.nlm.nih.gov/pubmed/17962031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2007.09.002
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