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A role for the p53 pathway in the pathology of meningiomas with NF2 loss

The neurofibromatosis 2 locus (NF2) is inactivated through mutation and loss of heterozygosity (LOH) in 40–65% of all sporadic meningiomas, while the role of the p53 tumor suppression pathway in meningioma initiation and progression is still unclear. This study aims to determine if a p53 codon 72 ar...

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Detalhes bibliográficos
Main Authors: Chang, ZeNan, Guo, Chin-Lin, Ahronowitz, Iris, Stemmer-Rachamimov, Anat O., MacCollin, Mia, Nunes, Fabio P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692701/
https://ncbi.nlm.nih.gov/pubmed/18974932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-008-9721-3
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