BMP-6 exerts its osteoinductive effect through activation of IGF-I and EGF pathways

We have recently shown that human recombinant BMP-6 (rhBMP-6), given systematically, can restore bone in animal models of osteoporosis. To further elucidate the underlying mechanisms of new bone formation following systemic application of BMPs, we conducted gene expression profiling experiments usin...

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Detalles Bibliográficos
Autores principales: Grasser, W. A., Orlic, I., Borovecki, F., Riccardi, K. A., Simic, P., Vukicevic, S., Paralkar, V. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer-Verlag 2007
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Original Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266664/
https://ncbi.nlm.nih.gov/pubmed/17634942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00264-007-0407-9
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