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BMP-6 exerts its osteoinductive effect through activation of IGF-I and EGF pathways

We have recently shown that human recombinant BMP-6 (rhBMP-6), given systematically, can restore bone in animal models of osteoporosis. To further elucidate the underlying mechanisms of new bone formation following systemic application of BMPs, we conducted gene expression profiling experiments usin...

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Detalhes bibliográficos
Main Authors: Grasser, W. A., Orlic, I., Borovecki, F., Riccardi, K. A., Simic, P., Vukicevic, S., Paralkar, V. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266664/
https://ncbi.nlm.nih.gov/pubmed/17634942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00264-007-0407-9
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