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Auranofin blocks interleukin-6 signalling by inhibiting phosphorylation of JAK1 and STAT3
Auranofin (AF) is a sulphur-containing gold compound. Because of its anti-inflammatory and immunosuppressive activities, AF has been widely used for the therapeutic treatment of rheumatoid arthritis. However, little is known about its mechanism of action. To elucidate the molecular mechanism underly...
Kaydedildi:
| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Blackwell Science Inc
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2266044/ https://ncbi.nlm.nih.gov/pubmed/17645497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02679.x |
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