Antiproliferative effect of gold(I) compound auranofin through inhibition of STAT3 and telomerase activity in MDA-MB 231 human breast cancer cells

Signal transducer and activator of transcription 3 (STAT3) and telomerase are considered attractive targets for anticancer therapy. The in vitro anticancer activity of the gold(I) compound auranofin was investigated using MDA-MB 231 human breast cancer cells, in which STAT3 is constitutively active....

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Bibliografiske detaljer
Main Authors: Kim, Nam-Hoon, Park, Hyo Jung, Oh, Mi-Kyung, Kim, In-Sook
Format: Artigo
Sprog:Inglês
Udgivet: Korean Society for Biochemistry and Molecular Biology 2013
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133824/
https://ncbi.nlm.nih.gov/pubmed/23351386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2013.46.1.123
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